The International Society for Computational Biology 10th Anniversary

PLoS Computational Biology is the official journal of the International Society for Computational Biology (ISCB), a partnership that was formed during the Journal’s conception in 2005. With ISCB being the only international body representing computational biologists, it made perfect sense for PLoS Computational Biology to be closely affiliated. The Society had to take more of a chance than similar societies, choosing to step away from an existing financially beneficial subscription journal to align with an open access publication as a matter of principle. To our knowledge, ISCB was the first major international scientific society to do so. Now, as PLoS Computational Biology reaches its two-year mark, ISCB simultaneously celebrates its tenth anniversary, having formed officially on June 18, 1997. We early presidents of ISCB reflect on the state of computational biology ten years ago, how far we have come since, and what thought-provoking future challenges might lie ahead with regard to innovations in publishing technologies.